Research Interests:

• Metal complexes of amino acids Schiff bases
• Chirality of complexed ligands
• Tripodal imidazolate Schiff base complexes of transition metals

Publications

Metal Induced Oxidation of Boranes. Synthesis of B₁₂H₁₆, the First Neutral Dodecaborane.  Brewer, C.; Grimes, R.N. J. Am. Chem. Soc., 1984, 106, 2722.

Metal Promoted Fusion and Linkage of B₅H₈-. 1-XB₅H₇- (X=D, CH₃). B₁₀H₁₃-, and (η⁵-C₅H₅)CoB₄H₇-.  Facile Routes to B₁₀H₁₄ and (η⁵-C₅H₅)₂Co₂B₈H₁₂ Isomers.  Brewer C.T., Grimes, R.N. J. Am. Chem. Soc., 1985, 107, 3552.

Metal Promoted Fusion of B₆H₉-.  Directed Synthesis and Structural Characterization of Dodecaborane(16), B₁₂H₁₆,  Brewer C.T.; Swisher, R.G.; Sinn, E.; Grimes, R.N. J. Am. Chem. Soc., 1985, 107, 3558.

Solvent Induced ¹¹B NMR Shifts in Metallaboranes and Metallacarboranes.  Venable, T.L.; Brewer, C.T.; Grimes, R.N. Inorg.Chem. 1985, 24, 4751.

Evaluation of the Formation Constant for an Imidazolate Bridged Complex of Co(TPP). Brewer, G.A.; Brewer, C.T. Inorg. Chim. Acta. Letters, 1985, 111,5.

Imidazolate Bridged Heterobinuclear Complexes Of Zinc(II)tetraphenylporphyrin.  Modeling Cyctochrome c Oxidase. Brewer, G.A.; Brewer, C.T. Inorg. Biochem. 1986, 26, 247.

Electronic and Solvent Effects in the Reaction of Zinc Porphyrins with a Metal Imidazolate Complex or 1-Methylimidazole. Cooper, J.B.; Brewer, C.T.; Brewer, G.A.  Inorg. Chim. Acta 1987, 129, 25-30.

Heteronuclear Imidazolate Bridged Complexes of Iron(III) Porphyrins and Copper(II). Relevance to Cytochrome c Oxidase. Brewer, G.A.; Brewer, C.T.  Inorg. Chem. 1987, 26, 3420-22.

Reduction of Fe(III) Porphyrin Hydroxides by Heterocyclic Aromatic Amines.  Brewer, C. Inorg. Chim. Acta 1988, 450, 189.

Synthesis and Chemical Reactivity of Copper(II) and Nickel(II)  Complexes of Imidazolate Containing Unsymmetrical Tetradentate Schiff’s Bases. Brewer, G.A.; Brewer, C.T.  J. Chem. Soc., Chem. Comm. 1988, 854-856.

Effect of Molecular Complexation of the Porphyrin Ligand on the  Axial Ligation of Fe(TPP)Cl. Brewer, G.A.; Brewer, C.T. Inorg. Chim. Acta 1988, 154, 67-71.    

Steric Effects in the Reactions of Zinc(II) and Iron(III) "Capped" Porphyrins. Brewer, G.A.; Brewer, C.T.  J. Chem. Soc. Dalton Trans. 1990, 843-847.

Substituent Effects on the Enthalpy and Entropy for the Axial Ligation  of Zinc Tetraphenylporphyrinates. Brewer, G.A.; Brewer, C.T.; Marbury, G.S.  J. Chem. Soc. Dalton Trans. 1991, 1377-1378.

Reaction of Sterically Hindered Imidazolate Complexes with Iron Porphyrins. Brewer, G.A.; Brewer, C.T. J. Chem. Soc. Dalton Trans. 1992, 1669-1672.

Magnetic Interactions in Dinuclear Complexes of Cr(salen)+. Brewer, G.A.; Brewer, C.T. Inorg. Chim. Acta 1992, 196, 1-5.

Spin Crossover in Heterodinuclear Iron(III) Schiff Base Complexes. Brewer, G.A.; Wang, R.; May, L.; Brewer, C. T.; Sitar, J. J. Chem. Soc. Dalton Trans. 1993, 151-155.

Structure and Magnetism of Electronically Distorted Iron(III) Schiff Base Complexes. Brewer, C. T.; Brewer, G. A.; Jameson, G.; Kamaras, P. May, L. J. Chem. Soc. Dalton Trans. 1995, 37-43.

Intermediate Spin Iron(III) Octaethyltetraazaporphyrinates with weakly coordinating anions: synthesis, characterization, and crystal structure.  Brewer, C. T.; Brewer, G. A.; Fitzgerald, J. P.; May, L.; Rheingold, A. L. J. Chem. Soc. Dalton Trans. 1996, 1249-1253.

Synthesis and Characterization of a Neutral, Low Spin Iron(III) Complex of a Hexadentate Tripodal Ligand Containing three Imidazolate Arms. Use as a Dinucleating Agent. Brewer, G. A., Brewer, C. T., Scheidt, W. R., and Mueller, I., Inorg. Chim. Acta, 1998, 278, 197-201.

Synthesis and Structural and Magnetic Characterization of Discrete Phenolato and Imidazolate Bridged Gd(III)- M(II) [M=Cu, Ni] Dinuclear Complexes. Brewer, C.; Brewer, G.; Scheidt, W. R.; Shang, M., Carpenter, E. E. Inorg. Chim. Acta. 2001, 313,65-70.

Synthesis and Structural Characterization of Copper Complexes of N₄ Tetradentate Schiff  bases Derived from N-alkylated 2-aminabenzaldehyde. Effects of Cyclization, Oxidation, and Dinucleation. Brewer, C. T.;  Brewer, G.; Kamaras, P.; Prytkov, S.; Shang, M.; Scheidt, W. R. Inorg. Chim. Acta, 2001, 321, 175-180.

Proton Control of Oxidation and Spin State in a Series of Iron Tripodal Imidazole Complexes. Brewer, C.; Brewer, G.; Luckett, C.; Marbury, G. S.; Viragh, C.; Beatty, A. M.; Scheidt, W. R. Inorg. Chem. 2004, 43, 2402-15.

Conformational Control of Spin State in Iron(II) Tripodal Imidazole Complexes. Brewer, C.; Brewer, G.; Viragh, C.; Patil, G.; Sun, Y.; Butcher, R. J. Inorg. Chim. Acta, 2005, 358, 3441-48.

Synthesis and Characterization of a Novel Gd(III)–Cu(II) Dinuclear Adduct. Brewer, C.; Brewer, G.; Shang, M.; Scheidt, W. R. Inorg. Chem. Comm., 2005, 8, 676-9.

Synthesis and Characterization of Seven-Coordinate Tripodal Imidazole Complexes of Iron(II) and Manganese(II). Brewer, C.; Brewer, G.; Butcher, R. J.; Carpenter, E. E.; Cuenca, L.; Schmiedekamp, A. M.; Viragh, C. J. Chem. Soc. Dalton Trans., 2005, 22, 3617-19.

Synthesis and Characterization of Cu(II) and Ni(II) Complexes of a Tripodal Ligand Containing Imidazoles. Brewer, C.; Brewer, G.; Butcher, R. J.; Carpenter, E. E. Inorg. Chim. Acta, 2006, 359, 1263-68. (Published on web 2005)

Synthesis and Characterization of Manganese(II) and Iron(III) d5 Tripodal Complexes. Effect of Oxidation State, Protonation State and Ligand Conformation on Coordination Number and Spin State.  Brewer, C.; Brewer, G.; Butcher, R. J.; Carpenter, E. E.; Cuenca, L.; Noll B. C.; Scheidt, W. R.; Viragh, C.; Zavalij, P. Y.; Zielaski, D. J. Chem. Soc. Dalton Trans., 2006, 8, 1009-19. (Published on web 2005)

Synthesis and characterization of a spin crossover iron(II)-iron(III) mixed valence supramolecular pseudo-dimer exhibiting chiral recognition, hydrogen bonding and pi-pi interactions.  Brewer, C., Brewer, G., Butcher, R.J., Carpenter, E.E., Schmeidekamp, A.M., Viragh, C. J. Chem. Soc. Dalton Trans, 2007, 295 - 298.

N - Alkylation of tripodal iron(III) imidazolate complexes:  reactivity and structure. Brewer. G., Brewer C., Butcher, R.J., Carpenter, E.E., May L., White, G. Inorg. Chim. Acta, 2007, 360, 2153-2161.

Supramolecular Assemblies Prepared from an Iron(II) Tripodal Complex Containing Imidazole-2-carboxaldehyde, tetrafluoroborate,and alkali metal cations (sodium, potassium, rubidium, and ammonium). Brewer, G.; Brewer, C.T.; Straka, A.; Alvarado L.; Butcher, R.; Viragh, C. Crystal Engr. Comm. 2009, 11, 2297-2307.

Synthesis and Characterization of Iron(II) and Iron(III) Complexes Derived from Tris(2-aminoethyl)methane. Brewer, G.; White, G.; Brewer, C.T.; Butcher, R.; Schmiedekamp, A.; Viragh, C.; Carpenter, E.E. Inorg. Chim. Acta. 2009, 362, 4158-4166

Synthesis and Characterization of Homo- and Heterodinuclear M(II)-M(III)’ (M(II) = Mn or Fe, M(III)’ = Fe or Co) Mixed Valence Supramolecular Pseudo-dimers.  The Effect of Hydrogen Bonding on Spin State Selection of M(II). G. Brewer, C. T. Brewer, A. Straka, R. Butcher, A. Schmiedekamp, C. Schmiedekamp, C. Viragh, Y. Yuzefpolskiy, P. Zavalij. Dalton Trans. 2011, 40, 181-94.

Synthesis, structure and supramolecular features of homonuclear iron(III) and heteronuclear iron(III)–cobalt(III) complexes, [FeH3L][ML](ClO4)3 (M = Fe(III) or Co(III). 2D sheet and tetrahedral arrays.Greg Brewer; Luigi J. Alvarado; Cynthia T. Brewer; Raymond J. Butcher; Jacqueline Cipressi; Carol Viragh; Peter Y. Zavalij. Inorg. Chim. Acta. 2014, 421, 100-109.

Correlation of nitrogen chirality, R or S, with metal chelate chirality, Δ or Λ, in a series of reduced tripodal Schiff base complexes.  A route to spontaneous resolution. Greg Brewer; Cynthia Brewer; Ray J. Butcher; Gene Thomas Robichaux; C. Viragh. Inorg. Chim. Acta. 2014, 410, 171-177.

Structural evidence of a ketimine as the product of an amino acid with an aldehyde. An intermediate in the racemization and transamination of amino acids. Greg Brewer; Cynthia Brewer; Ray J. Butcher; Matt Zemba. Inorganic Chem. Commun. 2016, 64, 35-38.